My modeling work focuses on the limbic system and cognitive-emotional interactions. I create rate-coded as well as spiking models of neuronal networks involving the amygdala, hippocampus, prefrontal cortex, thalamus, and basal ganglia. I also work with my labmates to develop tools and techniques for computational neuroanatomy, focusing primarily on primate tissue (macaque and human).
Publications
Wang, J, John, YJ, & Barbas, H (2020). Pathways for Contextual Memory: The Primate Hippocampal Pathway to Anterior Cingulate Cortex. Cerebral Cortex.
Joyce, MKP, García-Cabezas, MÁ, John, YJ, & Barbas, H (2020). Serial prefrontal pathways are positioned to balance cognition and emotion in primates. Journal of Neuroscience, 40(43), 8306-8328.
John, YJ, Bullock, D, Zikopoulos, B & Barbas, H (2018). Visual Attention Deficits in Schizophrenia Can Arise from Inhibitory Dysfunction in Thalamus or Cortex. Computational Psychiatry 2, 223-257.Zikopoulos, B, Liu, X, Tepe, J, Trutzer, I, John, YJ, & Barbas, H (2018). Opposite development of short-and long-range anterior cingulate pathways in autism. Acta Neuropathologica, 136(5), 759-778.
García-Cabezas MÁ, Joyce, MKP, John YJ, Zikopoulos B & Barbas H (2017). Mirror trends of plasticity and stability indicators in primate prefrontal cortex. European Journal of Neuroscience 46(8), 2392-2405
Zikopoulos, B, Hoistad, M, John, YJ, & Barbas, H (2017). Posterior orbitofrontal and anterior cingulate pathways to the amygdala target inhibitory and excitatory systems with opposite functions. Journal of Neuroscience, 3940-16.
García-Cabezas MÁ, John YJ, Barbas H, & Zikopoulos B (2016). Distinction of neurons, glia and endothelial cells in the cerebral cortex: an algorithm based on cytological features. Frontiers in Neuroanatomy, 10: 107 doi: 10.3389/fnana.2016.00107
Zikopoulos B, John YJ, García-Cabezas MÁ, Bunce JG, & Barbas H (2016). The intercalated nuclear complex of the primate amygdala. Neuroscience 330:267-90
John, YJ., Zikopoulos, B , Bullock, D & Barbas, H (2016). The Emotional Gatekeeper: A Computational Model of Attentional Selection and Suppression through the Pathway from the Amygdala to the Inhibitory Thalamic Reticular Nucleus. PLoS Computational Biology, 12(2), e1004722.
John, YJ, Bullock, D, Zikopoulos, B and Barbas, H (2013). Anatomy and computational modeling of networks underlying cognitive-emotional interaction. Frontiers in Human Neuroscience 7.
Bullock, D, Tan, CO, and John, YJ (2009). Computational perspectives on forebrain microcircuits implicated in reinforcement learning, action selection, and cognitive control. Neural Networks 22.5: 757-765.